The Institute of Child Health (ICH) is a postgraduate research institution which, together with its partner, Great Ormond Street Hospital for Children NHS Trust, contains the largest concentration of research expertise in the scientific basis of child health in Europe. Its standing is reflected in the Grade 5*A awarded in the 2001 HEFCE Research Assessment Exercise.

The Institute is committed to high quality postgraduate education and has a strong track record of training and support for its postgraduates. R&D is organised into a number of themes operating across the site which facilitate a high level of interaction between basic scientists, clinicians and population health scientists. The Institute is offering a number of research studentships for the academic year 2007-08 supported by the Child Health Research Appeal Trust and MRC.

Applicants selected for CHRAT or MRC funding will be able to choose from the following PhD projects (*denotes Principal Supervisor):

*Infection and Immunity*

Development of an enhanced lentiviral vector for gene therapy of ADA-SCID (Dr H Gaspar*/Dr M Antoniou/Professor A Thrasher)

Investigation of dendritic cell function in Severe Combined Immunodeficiency Dr S Burns*/Professor A Thrasher)

Bacterial viability: a critical factor determining the Dendritic cell responses to Neisseria meningitidis (Dr G Dixon*/Professor N Klein)

For further information about the ICH see our web site, www.ich.ucl. ac.uk. Applications are invited from committed individuals wishing to do research in a clinical context, and who expect to graduate with a UK 1st class or upper 2nd
class honours degree or equivalent.